Masterson was born on Long Island, New York, the son of Carol, a manager, and Peter Masterson, an insurance agent.

In 2006, Masterson took on a starring role in two independent film projects: Waterborne and Intellectual Property. Waterborne is a story about a group of Los Angeles residents who attempt to cope with life after a terrorist attack against their water supply. Waterborne premiered at the South by Southwest Film Festival and won the Audience Award. Chris embarked his second project, Intellectual Property, as the leading role and as a producer. Set in the midst of the Cold War, Masterson is Paul, an inventor who goes to great lengths to protect his inventions.

Before Waterborne and Intellectual Property, Chris also starred in the Wayans' Brothers film, Scary Movie 2 where he played "Buddy", a college student who has an uncanny knack for lacking social skills -especially when dealing with girls. He also appeared in Nice Guys Finish Last, a film directed by Robert B. Martin, Jr. Other film credits include My Best Friend's Wedding, American History X, Girl, Cutthroat Island, Dragonheart: A New Beginning, The Sunchaser, and Singles.

Additional television credits include the VH1 anthology series Back in Black in which he and Eric Roberts played serial killers, The Road Home and Disney's What's Up?for which he served as host. He has also guest starred on numerous shows, including Madtv, Touched by an Angel, Dr. Quinn: Medicine Woman Millennium, Murphy Brown, The Client, and the successful USA Network show The Dead Zone. Perhaps the most comedic was his guest appearance in three episodes of FOX's hit series That 70's Show where he played Todd, the manager of a cheese shop.

Theatre credits include Arcadia at the Mark Taper Forum in Los Angeles and the New York University production of The Sound of Music.

He was also voted into People Magazine's 50 Most Beautiful twice.

• Singles(1992)
• Cutthroat Island(1995)
• Campfire Tales(1997)
• My Best Friend's Wedding(1997)
• The Pretender(1998)(TV-Series)
• Girl(film) (1998)
• American History X(1998)
• Dragonheart: A New Beginning(2000)
• Living High
• Nice Guys Finish Last(2001)
• Scary Movie 2(2001)
• Hold On (2002)
• Wuthering Heights (2003)
• Waterborne(2005)
• Intellectual Property(Dark Mind) (2006)
• The Masquerade(2007)
• The Art of Travel(2007)
• Made for Each Other (2008)
• That 70s show

You can edit this page to add links to blogs, sites, and other information... If this page has a "PageType" set above - that will determine where the page is listed on SideReel. You can add text, a picture, links or more by editing the page... Check out the links above if you need help.