With fuel prices skyrocketing, the Planet Express crew sets off on a dangerous mission: to infiltrate the world's only dark-matter mine, source of all spaceship fuel. But deep beneath the surface lies a far stranger place... a medieval land of dragons and sorcery and intoxicated knights who look suspiciously like Bender. So park your hover-car and saddle up your unicorn for Futurama's grandest adventure yet: BENDER'S GAME!

In a comic-con 2007 cast reading previewing the four new movies featured in the Bender's Big Score DVD, it is shown that this chapter in Futurama's adventures will feature a Dungeons & Dragons-like setting where Bender dresses like a knight, Leela is a centaur and the Professor is a wizard. A teaser image depicts Fry as a Gollum-like creature, while the trailer shows him as a dragon. Amy will be appearing as the queen of the "Water Nymphos". Zoidberg will appear as a squid-like blob, similar to a beholder from Dungeons & Dragons (his head with tentacles much like his tendrils). According to David X. Cohen, the movie will be Futurama's "first real foray into the fantasy world as opposed to straight sci-fi".[4] The title appears to be a reference to the Hugo and Nebula award winning novel Ender's Game. The trailer also shows that much of the feature will spoof elements of Peter Jackson's version of The Lord of the Rings trilogy.

Additionally, Mom will make a return appearance, possibly as the main antagonist as the trailer seems to suggest, and the Planet Express crew apparently takes their ship to enter the "Space Demolition Derby", likely before the fantasy portion of the film takes place.

Guest stars will include George Takei and Rich Little reprising their roles as their own heads in jars.

A preview of Bender's Game is one of the bonus features on the Beast with a Billion Backs DVD.

According to the Beast with a Billion Backs commentary, the idea to spoof Dungeons and Dragons and the death of its creator, E. Gary Gygax, happened at around the same time, but are coincidences.