Czuchry was born in Manchester, New Hampshire and grew up in Johnson City, Tennessee. His father, Andy, is a professor at East Tennessee State University and his mother, Sandra, is a homemaker. He has two brothers, Mike and AJ, and a sister, Karen. His height is 5' 10" (1.77 m). He graduated from Science Hill High School in 1995. Czuchry graduated with honors in 1999 from the College of Charleston with a Bachelor of Arts degree in History and Political Science. He won the Mr. College of Charleston pageant in 1998. Czuchry went to school on a tennis scholarship, was captain of the men's tennis team, and was an NCAA ranked player in the Southern Conference. Czuchry took one theater class in college, and his professor encouraged him to change his major to drama. Additionally, Czuchry studied acting with Belita Moreno, star of the comedy series George Lopez.