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Samantha Who? News

Christina Applegate is Back with 'Samantha Who'
Watch a sneak peek of Season 2 Episode 10 ''My Best Friend's Boyfriend''
Billy Zane Reunites with Christina Applegate on 'Samantha Who?'
Christina Applegate Begins Breast Cancer Treatment
More ABC Starter Kits: Get Ready for the Fall Season!
Samantha Who? Returns Tonight
Test Your Samantha Who? Love
Watch Now Online: Last Night's New SYTYCD, Burn Notice, Royal Pains, and More! - Featured