In the movie, when a $5 billion NASA probe disappears into an intergalactic wormhole, the agency recruits Ham III (Andy Samberg), grandson of the first chimpanzee in space, to help retrieve the wayward craft. But Ham is a free-spirited circus performer more interested in zero gravity high jinks than living up to his illustrious heritage. The simian slacker becomes a reluctant hero and learns the true meaning of courage as he and his crewmates, the fearless Lt. Luna (Cheryl Hines) and their uptight commander, Titan (Patrick Warburton), risk everything in an effort to save the peaceful inhabitants of a distant planet from the evil dictator Zartog (Jeff Daniels). |||| Jeff Daniels, Stanley Tucci, Cheryl Hines, and Andy Samberg lend their voices to this computer-animated comedy following the descendants of the first chimps in space as they blast off for fun and adventure on a far-away planet. Ham III (Samberg) is the grandson of Ham, the first-ever chimp astronaut. This ne'er-do-well chimp may not be the most qualified ape for the job, but a scheming senator (Tucci) has recruited him for a most dangerous mission. It seems that a powerful tyrant (Daniels) has overtaken an alien world, and now it's up to Ham III and his trusty simian crew (Hines and Patrick Warburton) to help overthrow the deep-space despot. Perhaps with some training from Ham III's mentor (Kenan Thompson) and the help of a friendly alien (Kristin Chenoweth) this fearless group of anthropoids can make the universe a safer place for aliens and humans alike.

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