Wednesdays, 9:00 PM ET on The CW
Jensen Ackles and Jared Padalecki star as Dean and Sam Winchester, two brothers searching for the meaning behind their mother's death at the hand of a demon, and their father's mysterious disappearance.
This show has had it's fair share of problems but overall they can be overlooked as Sam 'n' Dean are without a doubt the best TV duo in existance. Sexy, smart, funny and not above taking the Michael out of themselves, Jared Padaleki and Jenson Ackles on screen chemistry is beyond reproach. When they fight, when they're friends and all the brotherly interaction is believable. Also loving both cass and crowley as the literal angel and devil on the boys shoulders, mischa collins and mark shepard who bring both humour and honesty to the characters.
1,931 show lists