Alex Beck (Cluzet) is a doctor who has slowly been putting his life back together after his wife Margot was murdered by a serial killer. Eight years on, Alex is doing well enough until he finds himself implicated in the murder of two people, with plenty of evidence pointing to him as the killer even though he knows nothing of the crimes. The same day, Alex receives an e-mail that appears to be from Margot (Marie-Josée Croze), which includes a link to a live surveillance video clip that features his late wife looking alive and well. The message warns Alex that they are both being watched, and he struggles to stay one step ahead of the law even as a gang of strong-arm men intimidate Alex's friends into telling whatever they might know about him. Alex's sister Anne (Marina Hands) persuades her well-to-do wife Hélène (Kristin Scott Thomas) to hire a respected attorney, Élisabeth Feldman (Nathalie Baye), to handle Alex's case. When a warrant is issued for Alex's arrest, he goes on the run while he and his lawyer struggle to find out the truth about the murder as well as Margot's reappearance.

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