In this Sherlock Holmes mystery, the great detective and Dr. Watson help a young woman who has received a giant pearl from a mysterious man. The woman, to whom Watson is very attracted, is also searching for her father who has mysteriously disappeared. Holmes and the Dr. first go to the home of a flamboyant fellow in South London. This man too is being harassed by the mysterious stranger. This leads the sleuths to a one-legged criminal and his assistant, a dwarf. The story climaxes with a thrilling motor boat chase down the Thames.

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