Two teenage nerds, Gary (Anthony Michael Hall) and Wyatt (Ilan Mitchell-Smith), unpopular and unable to meet girls on their own, use a computer to design the perfect woman. They feed various data (images mostly) into Wyatt's computer. Lacking sufficient processing power, they hack into a US Government mainframe and use its power to create a computer simulation of "the perfect woman" in order to place her in "real life sexual situations" and see how she reacts. A bizarre electrical storm (à la Frankenstein, their inspiration) follows, and they find themselves unable to shut the computer off. Mysteriously, the result is "Lisa" (Kelly LeBrock), a real-life woman (who emerges from a red fog in the bathroom). She is a sexed-up but kind-hearted "80's babe" with Einstein's IQ, David Lee Roth's attitude and inexplicable supernatural powers. Self-aware from the moment of her creation, Lisa sets about revealing their inner coolness, transforming Gary and Wyatt from nerds into men through a series of wacky and bizarre adventures. Using her magic powers, she takes them to a Blues Club, confronts Wyatt's domineering older brother Chet (Bill Paxton), and throws a giant party at Wyatt's upscale home. In the end, the boys get no sex from their mentor, but are seemingly on the path to a relationship with two cute girls their own age. The movie ends with a group of high school boys in gym class, talking and joking around as two somewhat nerdy boys, similar to how Gary and Wyatt were at the beginning are given the spotlight. Their gym instructor appears and turns out to be none other than Lisa herself. As the boys look on in stunned silence, the two aforementioned ones in particular, Lisa orders them to "drop and give me twenty". The boys all slap themselves on the head and collapse unconscious to the floor. Lisa smiles at the camera and winks.

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