The series is set in the fictional town of Bradfield, assumed to lie within West Yorkshire. However, the filming location is the cityscape and surrounding countryside of Newcastle upon Tyne and Northumberland. Each episode usually involves a serial killer. The offbeat Asperger-like behaviour of Robson Green's Tony Hill is rather disconcertingly reminiscent of the behaviour of the traumatised detective Dave Creegan, the character that Green played in the 1997 ITV series Touching Evil.

• Wire in the Blood at itv.com
• BBC America's Wire in the Blood Page
• Robson Green - Wire in the Blood

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