Alien vs. Predator 3

Brothers Greg and Colin Strause had this to say about a third film - "AVP-R" definitely leads into another film. While "AVP-R" takes place in an American Midwestern town, for the next film, they want to take the action back into space. As a matter of fact, they said that 20th Century Fox has no choice other than to agree to take it back into space following "AVP-R."