Grey's Anatomy: What's Next for Mer and Der?

Inside Meredith and Derek's bedroom on the Grey's Anatomy set, a very naughty Patrick Dempsey climbs on top of his costar and friend of six-plus years, Ellen Pompeo, and admonishes there is to be "no thrusting." Joking that he's been "doing steroids" over his summer break, the pumped-up star plants one on Pompeo's lips before making an accusation that catches his leading lady off guard: "Did you just have a jelly doughnut?"

The lighthearted high jinks are welcome on a set that has been plagued with discontent for far too long. "I'm glad for the other folks who have gone on to do things that make them happy," says costar Sara Ramirez (Callie), referring to the departures of Isaiah Washington, T.R. Knight and Katherine Heigl. "But the people who are here now are here because they want to be."

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