From USA Today:
The show chronicles the ups and downs of Jackie Peyton, a tough nurse in a New York City hospital. Though her instincts are great on the job, her personal life is a bit of a mess: She pops pills, occasionally removes her pants during office hours and isn't the easiest person to get along with.
It took me awhile to get used to the show's tone, but I was so surprised by the ending that I'll keep watching, just to see where it leads.
Nurse Jackie debuts June 8 at 10:30 p.m. ET, right after the season premiere of Weeds."