2010's Best Episodes: Grey's Anatomy's Crazed Gunman and Lost's Emotional Farewell

It was a great year for TV, which made it very difficult to choose the top 25 episodes of 2010. Recalling and, in some cases, rewatching the stand-out moments was a holiday treat. We got our first glimpse of a bespectacled Clark Kent and saw Snooki pummel Angelina. We wept as Jack Shephard took his final breath and cheered as Leslie took down a mischievous rodent wreaking havoc in Pawnee. Here's the fourth batch of TVGuide.com's weeklong countdown of the year's best episodes.

10. "Sanctuary/Death and All His Friends," Grey's Anatomy

A shooter roamed through the halls of Seattle Grace, killing off many of the doctors we have come to know and love, and leaving several others on death's door, including Derek Shepherd. After Meredith offered to sacrifice herself to protect the other doctors and subsequently had a miscarriage, the veteran series was taken to a new, deeper level.

9. "Peter," Fringe

This flashback hour not only expanded the show's mythology of the alternate universe, but revealed the painful backstory behind Walter's decision to kidnap Peter's doppelganger after "his" 7-year-old Peter died. John Noble's sublime dual turn delicately balanced the audacity and distress of a grieving parent. This episode also marked the debut of '80s-style opening credits.

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