'Grey's Anatomy': Nia Vardalos and Peri Gilpin to Guest Star (Exclusive)

A new pair of sisters will be joining Meredith and Lexie on Grey's Anatomy.

My Big Fat Greek Wedding star Nia Vardalos and Frasier's Peri Gilpin will guest star on an episode of the ABC medical drama, The Hollywood Reporter has learned exclusively.

Vardalos, whose TV work includes stints on Cougar Town, Drop Dead Diva and My Boys, will play Karen Winterbottom, while Make It or Break It's Gilpin will play her sister, Marcy, on an episode of the Shonda Rhimes series. The bickering sisters will come to Seattle Grace during an episode slated to air in mid-January. Read More...



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