Her disease practically has wrecked any chance at a normal personal and professional life, though at the start of the second season of Homeland, it appears like Carrie is closer than ever to having both. She's teaching and, since it's Thursday, she's cooking dinner for the family (with vegetables from their vegetable garden).
There's something more potentially damaging to both of her lives than her bi-polar disorder, however, and that's her past job at the CIA.
Sure, part of Carrie's reluctance to go back on a mission was anger and spite for how she was drummed out. But the main reason is because she felt since she was so, so very wrong about Brody that she had no business being there.