I don't think it's any secret that Katherine Heigl has been unhappy playing Izzy. And there was talk that Izzy's illness would give the actress an exit strategy.
Is it better that Izzy die or live? On one hand, I'm kinda sick of her, but on the other hand if McDreamy is going to recover at all from being in the kill zone, shouldn't the writers have him save Izzy? What do you think?