From playing a doctor to portraying a patient...
Sarah Wayne Callies will guest star on an upcoming episode of House. Not much is known about the role, except that the actress will likely come down with a challenging case of some disease that will take almost an hour to diagnosis.
Callies starred on Prison Break as Dr. Sara Tancredi for most of that show's four-season run, except for a few episodes that saw the character supposedly die from a decapitation.
It's safe to assume her Patient of the Week on House won't suffer from that problem... but you never know.