Judging from the comments on our Worst Relationships of Grey's Anatomy slideshow (see below), the pairing of Mark Sloan (Eric Dane) and Lexie Grey (Chyler Leigh) is not really popular with the show's fans. As things currently stand, however, Little Grey remains to be one of the first women to have tamed McSteamy and shown him the way (to fidelity).
Perhaps to the chagrin of these fans, TV Guide reports that there'll be plenty more to see of this couple, which can very well be this season's dark horse relationship. Reportedly, this will be due in large part to Sloan finally accepting the relationship and embracing the fact that he is committed to it.
However, the relationship will be put to the test as Lexie's father returns to the scene pretty soon.