1 of 10
Katherine Heigl, Grey's Anatomy
Sure, Heigl landed a couple of choice movie parts immediately after burning her bridge to Shondaland, but she became box office poison and her two attempts to resurrect her TV career have been... disappointing.
2 of 10
William Petersen, CSI
Petersen probably doesn't need to work another day in his life, after pulling in a reported $600,000 per episode during his final season on the long-running show (of which he also was an executive producer). Which is good, because he hasn't. At least not in anything notable.
3 of 10
Jessica Brown Findlay, Downton Abbey
We love Lady Sybil, but we'll never forgive Findlay for leaving the show in its third season. She might not forgive herself either. Despite its incredible cast, the slightly creepy Winter's Tale did not become a thing.
4 of 10
Josh Charles, The Good Wife
Charles has popped up in some pretty fun guest spots on TV (notably on Inside Amy Schumer and Masters of Sex), but walking away from a hit CBS drama? Boy, you cray.
5 of 10
T.R. Knight, Grey's Anatomy
By all accounts, the atmosphere during the Isaiah Washington meltdown was not great, but Knight's decision to leave the Shonda Rhimes drama so soon seems even more suspect as the series races toward its 14th season.
6 of 10
Topher Grace, That '70s Show
He's had supporting roles in films since leaving That '70s Show after its seventh (of eight) seasons, but nothing as big as Eric Forman.
7 of 10
Nina Dobrev, The Vampire Diaries
By far Dobrev's highest-profile gig since 2015 was her return to TVD for the show's finale.
8 of 10
Christopher Meloni, Law & Order: Special Victims Unit
Failed contract negotiations marked the end of the Stabler/Benson partnership. Meloni's biggest post-SVU TV project, Surviving Jack, lasted just eight episodes.
9 of 10
Mischa Barton, The O.C.
Barton departed the show after the third season finale, at the height of the FOX series' popularity. But she was unable to capitalize on that momentum, becoming another Hollywood trainwreck.
10 of 10
Sandra Oh, Grey's Anatomy
Oh, Sandra! Why? This talented actress can have whatever kind of career she wants (and right now that appears to be small indies and other supporting TV roles), but leaving Meredith like that? Luckily, Oh made her exit without wrecking her relationship with the producers, so there's a chance she'll make a return appearance.
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