A 300-year-old haunted hospital in Boston is the setting of this horror-filled series, in which a young doctor tries to unravel mysterious and often deadly happenings. Based on a miniseries from filmmaker Lars von Trier.
Barney Wheelock (Nigel Bennett) is almost killed, and has a near-death experience, just after being admitted. Dr. Elizabeth Baines (Leah Pinsent), an old friend of Dr. Cullen, is at the hospital speaking on the "white light" near death experience. Wheelock becomes possessed by "Roger" and dangerous, kidnapping tattooed nurse Kim Peretti (Cecile Cristobal) before killing his wife Calvette (Anik Matern) and their two sons. Roger then possesses Kim and goes after Dr. Sterling. It is revealed that "Roger" is an old "god of the dead" working through nurse Karen Waverly (Ann Day-Jones) and has gone after Dr. Baines as the next victim. Dr. Cullen is attacked in the process, but saved by Dr. Grace. The episodes closing shot reveals that the ancient symbol used to represent "Roger" is also used as the logo for All Souls Hospital.
Experiments on five female athletes; Jolene Martin, Sierra Wilson, diver Anna Markham (Michelle Carroll), volleyballer Belinda Karch (Maria Bertrand), and runner Abigail "Gabby" Maine (Karen Cliche) have been undergoing experiments by Dr. Henry Lohman (Ken Jenkins) at the All Souls Sports Medicine Clinic. The first three are dead, and in trying to help Gabby the doctors find out that Belinda has apparently aged from twenty to over ninety as a side effect of the experiment. It is revealed that all five are Dr. Lohman's "daughters" via a genetic breeding experiment, but that the deaths are from an assistant giving the girls experimental DNA treatments without Lohman's knowledge.