Special Agent Joe Pentangelo of the ASPCA rescues a fearsome-looking mastiff from a rundown car lot in Brooklyn. The dog, named Kane, suffers from "cherry eyes," a painful infection of the eyes. On Staten Island, Special Investigator Annemarie Lucas is called to rescue a dog called Maximus. It's the start of another long and emotional search for that someone special; someone prepared to give him a new home and a new life. With Maximus, there's just one problem ... he's a pitbull. These dogs are normally difficult to adopt out, but the ASPCA is tireless in looking for a family right for him.