Directed by Demi Moore and written by Stephen Godchaux, “Five’s” opening film, Charlotte, takes place the night in July 1969 when man first walks on the moon, and when a young Pearl (Ava Acres) is more concerned about why her family is not letting her see her mother, Charlotte (Ginnifer Goodwin), who lies in her bedroom dying from breast cancer. When she sneaks in to see and ultimately say goodbye to her mother, Pearl develops a lifelong passion to help others afflicted with the disease and eventually opens an oncology clinic where she will treat the women we meet throughout “Five.” Charlotte also stars Jeanne Tripplehorn, Josh Holloway, Annie Potts, Jennifer Morrison and Bob Newhart.