Hit and Miss stars Chloe Sevigny (Big Love) as a contract assassin, Mia, who also happens to be a pre-op transsexual. Making for a more chaotic life, she learns she fathered a son more than a decade ago.
Mia finds herself being forced to use her professional knowledge to cover up what Riley has done. She feels uncomfortable though with receiving help from Eddie, who she still cannot fully trust. Ben's confusion about his attraction to Mia increases after he finds out more about her past.