60 minutes

We've all witnessed the national impact of an Amber Alert when a child goes missing, with police and media mounting a major operation to find them. Unfortunately, cases are rarely investigated with the same urgency when the missing person is over the age of 18 or considered a possible runaway, leaving devastated loved ones lost and alone in their search for answers. "Last Seen Alive" follows the emotional and action-packed journeys of 12 families-turned-detectives as they chase down leads, interview potential witnesses, and travel cross-country in the hope of reuniting with their recently missing relatives. Beginning with the moment the person was last seen alive, episodes chronicle the search efforts of a desperate family with everything to lose, aided by a skilled private investigator determined to turn chase down every lead. Though the status of these investigations could change at any minute, many concluded filming with heart-warming resolutions, some with tragic endings, while others remain open and active to this day.