The Brinkley's are about to welcome another new addition to their household on this week's episode of Up All Night . Dean Winters ( 30 Rock, Rescue Me ) guest stars as Chris' ( Will Arnett ) older brother, and it doesn't take long for their competitive ed more

Complications are coming up for Christina Applegate 's Reagan Brinkley both at work and home on NBC's Up All Night . Actress Eve Best , who steals every scene she's in as Nurse Jackie 's Dr. Eleanor O'Hara, has landed a role equivalent to Alec Baldwin's b more

Up All Night  “Rivals” Episode 13 airs Thursday January 19 on NBC (8-8:30 p.m. ET). Episode Synopsis: Reagan (Christina Applegate) and Ava (Maya Rudolph) are thrown into a spiral when rival talk-show host and former friend of the show, Shayna (guest more

Up All Night  “New Year’s Eve” Episode 12 airs Thursday January 12 on NBC (8-8:30 p.m. ET). Episode Synopsis : – Reagan’s (Christina Applegate ) extreme competiveness comes out at a New Year’s Eve game night , much to Chris’s (Will Arnett) embar more

Alanis Morissette will guest-star on an upcoming episode of Up All Night , TVGuide.com has confirmed. The "You Oughta Know" singer will portray... http://www.tvguide.com/News/Up-All-Night-Alanis-Morissette-1040710.aspx?rss=breakingnews

Blythe Danner returned as Reagan's mother for the Christmas installment of 'Up All Night' (Wed., 8PM ET on NBC). She arrived to find her daughter in full OCD mode trying to outdo the neighbor's Christmas decorating in order to get the same reaction from h more

Up All Night  “First Christmas ” Episode 11 airs Wednesday December 7 on NBC (8-8:30 p.m. ET). Episode Synopsis : – Reagan (Christina Applegate ) will do anything  to make Amy’s first Christmasperfect, even if it means getting help fro more

Molly Shannon 's guest appearance on NBC's Up All Night is now officially a recurring role. I've just learned that Molly has been invited to reprise her single-mom character, Nancy, early next year. The new storyline will find Nancy, an incompetent ass more