Me, Myself & Irene is a 2000 comedy film directed by the Farrelly Brothers, and starring Jim Carrey and Renee Zellweger. The story revolves around a nice guy cop (Carrey) with multiple personality disorder, who must protect a woman (Zellweger) on the run from a corrupt ex-boyfriend and his associates. Chris Cooper, Robert Forster, Richard Jenkins, Daniel Greene, Anthony Anderson, Jerod Mixon, and Mongo Brownlee co-star. Tony Cox, Traylor Howard, Anna Kournikova and Cam Neely have cameo roles. The film was released on June 15, 2000 and it's Tagline is: From gentle to mental.