The plague struck Bluebell in "Lovesick Blues," this week’s episode of Hart of Dixie, and despite voting to put themselves under quarantine, the town was ravaged by it. Magnolia didn’t even get to throw her wild party!
She can blame Wade; he brought the flu into town after sneaking past quarantine because his ex-girlfriend tried to jump him after their old band had a reunion gig. Because he didn’t want Zoe to take care of him, he infected almost the entire town, eventually including Zoe herself, which led to him having to take care of her. They are really selling me on Wade and Zoe these days, maybe because they’re going out of their way to turn George into less of a romantic lead and more of a wacky townsperson who happens to be really good looking.