What about a movie, or a two two part episode.
Big basket ball game at Tree Hill high, big explosion, Brooke and Jamie left inside, Brooke feared dead.
Episode part 1
Basket ball game Brooke Takes Jamie to the toilet, big explosion.
Episode part 2
Everyone gets out, Brooke and Jamie not to be seen, Lucas runs in to the burning school, and comes out of the smoke with Jamie in his arms. Another explosion, everyone scared and screaming. Brooke may be dead until, some one else who was in the building comes out with her in his arms but who is it, see in next episode.