Wilson becomes the center of this week's episode when an old patient and friend experiences paralysis in his arm. As his condition worsens, Wilson must make some moral decisions that make it difficult for him to differentiate between patient and friend. Meanwhile, Cuddy goes house-hunting for a new place for her and Lucas.
Wilson wakes to the sound of House playing George Michaels' "Faith." He asks House to tone it down because he needs to get sleep before he goes hunting. House comes in and says his hunting pal is a "self-important jerk." We cut to Wilson and his pal Tucker (Josh Malina) hunting turkey - or trying to, at least. Wilson then takes a chemo bag, stabs it up against a tree and writes "Year 5" on it. It represents Nov. 30, 2004: the day Tucker was projected to die with leukemia but was saved by treatment. Tucker shoots the bag and it explodes into smithereens, but the celebration is cut short when a gunshot goes off in Wilson's direction after Tucker drops his gun from losing feeling in his arm.
As a friend and former patient, Wilson takes the case and reports to Tucker and his new, much younger girlfriend Ashley, that there are no signs of a stroke or a relapse of cancer. But Wilson notices Ashley has a cold sore and is convinced her infection spread to Tucker's spine causing Transverse myelitis. He starts Tucker on treatment and goes to House to brag to him about his "House moment," but House bursts his bubble by saying Tucker has cancer. House is so confident his friendship is clouting his judgment that bets $100 that it's cancer. Wilson accepts, refusing to believe it.
Wilson Plays House
Tucker asks Wilson to call his family to come be with him considering they aren't too thrilled with the fact he's dating a zygote. Tucker's ex-wife Melissa and daughter finally agree to come.
The medicine doesn't seem to be working, so Wilson hits up House's team for some help. Thirteen comes up with fungus balls in his lungs and Wilson runs with it. But unfortunately, Chase finds it's much more than fungus causing Tucker's symptoms. It winds up being another kind of leukemia in his head. House wins.
Wilson tells Tucker and his family that he has a 90 percent chance for a cure if they remove the cancer and treat with chemo. Tucker knows Ashley is wishy-washy about making important decisions, so he has his ex-wife become his proxy.
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