Keiko O'Brien operates a school on Deep Space Nine for the station's children, most of whom are Bajoran. She is accused of blasphemy by Vedek Winn, one of the spiritual leaders of Bajor, as she explains the scientific background of the Bajoran wormhole. Winn feels that, as the Bajoran civilization sees in it a religious symbol (the "Temple of the Prophets"), the Bajoran children should be taught this theory in preference to Starfleet physics and astrobiology. After a bomb is detonated in the school, Commander Sisko is forced to seek help from Vedek Bareil, a Bajoran spiritual leader who has a different ideology than Winn.
The episode is significant in that it lays the groundwork for the tension on Bajor that would be more fully realized in Deep Space Nine's second season. However, it also begins to bring Sisko and Major Kira closer together, as they realize that they both have Bajor's best interests at heart.