Now that the computer with contact info for other Fifth Column members has fallen into the wrong hands, the lives of the Fifth Column members are in danger, prompting Erica, Father Jack and Hobbes to take drastic measures to protect them in the V episode "Heretic's Fork."
When we last saw V, Erica's team captured the assassin who killed Alex Caruso but realized that he's human and not one of the Visitors. The man refused to spill any beans but revealed why he did what he did: "Because we can't win."
The assassin's answer seems to be the main issue on V and almost episode we get tidbits of clues as to whether humans can really win against the Visitors. Hopefully tonight we get more answers as Chad rolls the camera for Prime Focus and begins the process aboard the Mothership's Medical Bay to have his aneurysm taken out.