The show followed the lives of a group of flight attendants working for the fictitious Regency Airlines. Jess Jameson (Rose Jackson) and Maggie Reynolds (Kristin Bauer) are roommates and work together and live in the trendy South Beach section of Miami, Florida. Their other friends included: Paul, who was gay; Randy, a "ladies man"; Lenora, a former flight attendant; MacArthur, the bartender of Mambo Mambo, the restaurant the gang hung out at; and Captain Rex Parker. The show was ultimately canceled due to low ratings (due to being scheduled against the Top 10 hit The Single Guy) and was criticized as being "Friends on a plane".