Rated: TV-MA for Adult Content (AC) and Adult Language (AL) Tonight's episode is Live from L.A. Tonight, Bill welcomes: * Former Rep. Harold Ford Jr. (D-TN), who lost a bid for the Senate in the 2006 election to Bill Frist, partly due to a famous attack ad. * Sean Penn, Oscar-winning actor and activist who has independently visited Baghdad and New Orleans in humanitarian missions. * Garry Shandling, Emmy-winning comedian, most famous for "The Larry Sanders Show." Bills guests via satellite: * Tommy Thompson, former Governor of Wisconsin and Health and Human Services Secretary who announced a bid for the GOP nomination for President. * Dr. Sanjay Gupta, neurosurgeon most famous for being a medical correspondent for CNN and CBS.