David 'Brown' boards a Boeing 747 plane to travel across the country in pursuit of a cure for his metamorphosis. The airline captain and a flight attendant have planned the theft of a priceless Egyptian exhibit from the plane's cargo hold. After dealing with the pilot and flight attendant, David is forced to land the plane during one of his transformations into the Hulk.
Note: Brandon Cruz, Bill Bixby's co-star on The Courtship of Eddie's Father (1969–1973), makes a guest appearance.