Simon and Cad use one of Simon's time bombs to head back in time to Plymouth Rock in 1621 where they destroy the Indian village and the Pilgrims settlement. In present day, Sweet Polly and Underdog head for the two villains basement lab where they find Simon's hidden cache of time bombs in a secret compartment behind a bookcase. They use the time travel device to land in 1621 Plymouth Rock... only to discover that a war between the Pilgrims and the Native Americans has started and that Simon and Cad have returned to the 20th Century.