While filming an episode of Childrens Hospital, Dixie Peters (Lake Bell) and Lynn Williams (Erinn Hayes) have a romantic rivalry over the director, David Wain (David Wain), the latter being divorced from him and the former now married to him. Meanwhile, Rob Heubel (Rob Huebel) tries to hide his medical condition from the show's crew in order to keep his job with the help of Cutter Spindell (Rob Corddry).