As the fourth season opens, All Saints has been taken over by a multinational corporation and placed in the care of an innovative no-nonsense doctor who is revved up about making changes to the hospital and staff. Meanwhile, Kevin has moved to a new apartment, but is seeking to reconcile with Jackie. As for Jackie, she runs into problems when a guy she picked up has a heart attack in her home. Later, back at the hospital, Mrs. Akalitus is given an ultimatum by the new management.