“Death at Jamestown” speculates on the causes of what narrator Liev Schreiber calls “the strange and sudden afflictions” that took the lives of settlers of Britain's first permanent American colony between 1607 and 1610. Famine, hostile Native Americans and diseases such as “the bloody flux” could certainly have taken their toll. There was also internal strife. Frank Hancock, a pathologist, even suspects that Catholic agents could have poisoned Protestant settlers.