As Nozomu arrives in the middle of their meeting with the Master Head about other Headders on Earth, the Gosei Angels lose the reception as they were about to know how to summon them. After Hyde convinces the team they'll find the Headders eventually, Nozomu reveals a "Genius Cold" epidemic at his school as the gang decide who gets to train and who goes grocery shopping. Losing to the others, Hyde and Agri head off with the former running the later dragged across every grocery store to pick the best food from each. Hyde hears a female voice. Becoming Gosei Blue, he saves her from the Bugntes Alien Ucyuseruzo of the Influenza as he attacks her for following him. Though his Seaick Bowgun had no effect, Gosei Black's arrival forces the Universal Insect Monster to retreat while the woman comes to and sees the two Goseigers revert in front of her as Hyde asks why she was following Ucyuseruzo. Introducing herself as Dr. Renko Shikishima, she takes Hyde and Agri to her son Kenichi before he transforms into a Bibi Soldier as a side effect of the Genius Cold. While Alata and the girls are holding off the student-turned-Bibi Soldiers, after running off, Agri watches a broadcast of Renko announcing the creation of an antidote. Arriving as she is attacked by Ucyuseruzo, Agri realizes "Renko" is actually Hyde in disguise as Gosei Blue musters enough strength to use the Landick Ax to weaken Universal Insect Monster before using the Seaick Bowgun to take enough of his hemolymph for Renko to develop the antidote. The others arrive after holding the confining the converted Bibi Soldiers, forming the Gosei Buster to defeat Ucyuseruzo. After being enlarged by the Bibi Bugs, Ucyuseruzo overpowers Gosei Great with its own sword until Gosei Blue calls in the Seaick Brother Headders as they combine unto Gosei Great to form Seaick Gosei Great and destroy Ucyuseruzo. Later, as every child is cured to the Genius Virus and Renko, Hyde and Agri nearly reached an understanding until the former opens his mouth about the latter's weapon needing maintenance.