I had high hopes for this going in: speculative fiction comedies are rare, and this comes with the pedigree of the creator of 3rd Rock from the Sun, which I enjoyed.
However, this simply doesn't hold up on any level. The entire comedy is based on shallow, lazy tropes about "how men and women are," which are sexist, boring, and untrue. The first episode was all I could get through, and usually I'll stick with shows for a while to see if they get good, but I couldn't even imagine this possibly going anywhere I would like, and reviews indicate it just gets worse, they just deepen into even more hateful parodies of the gender binary.
I couldn't even take the premise seriously because simply no attention was paid to any kind of realism. Humanity was wiped out by a "virus," but there were no corpses anywhere, just a big empty playground of wish fulfillment. This is like every criticism of the zombie genre being about wish fulfillment for beta males who want to steal stuff and have hyperviolence, only for even more pathetic beta males who don't even want to blow up zombies. It isn't remotely relateable unless you're a pathetic white guy who sits around being entitled and wishing you could do anything you want like a big unwatched child, and generally hating women while being angry you can't get any.
There are also apparently no animals in this world--raccoons and coyotes don't despoil the supermarket foods, there are no packs of feral dogs, as you'd expect after a virus affecting humans. Nuclear power plants don't melt down without maintenance. There's no respect for the genre, just "what if I could do anything I want" with a few jokes about how women are awful but ya just can't live without them. I wasn't sure if this was written in 2015 or 1885, because the mindset of women (notably, white women, but in the genocide that was apparently also part of the wish fulfillment, only white people survived the end of the world) are a civilizing force on bestial men, all rules and order and properness comes from women. The last woman on earth couldn't be hairy-armpitted and leg-bearded and FINALLY free to break all the oppressive rules that don't benefit her--oh no, because rules are in a woman's blood, and only exist to oppress white men...who in reality are the main beneficiaries of every rule and system.
The first episode ends with these two parodies of their genders deciding to get married, clearly settling into a lot of old-timey jokes about how awful heterosexual marriage is because they can't stand each other. I really don't know how they took such an interesting premise and managed to be this small-minded and boring, how they went so far to break out of the status quo only to underline it, and insist the status quo is the only quo and just how things are and must be.
And most damning of all, I didn't laugh once. What was I supposed to laugh at, the "oh, that's SO true" fallacy of how men do plumbing with duct tape even though they don't know what they're doing, because women are completely helpless and depend on their sad bumbling useless asses? How a man about to kill himself because he had no one to talk to, when interrupted by the knowledge that another human was alive in the world, within forty-five minutes of hearing her speak remembered how much he hated women talking? I wish he'd just killed himself, then he could have all the silence he wanted. This show was AWFUL, just sad, painfully unimaginative, and pathetically lazy. Tell a story about the last man on earth when you have anything of worth to say about the nature of humanity.
For a speculative fiction comedy about being the last surviving human that's ACTUALLY FUNNY, do yourself a favor and watch Red Dwarf.